review hibiscus.pdf

of 9
All materials on our website are shared by users. If you have any questions about copyright issues, please report us to resolve them. We are always happy to assist you.
Transcript 4719   Pekamwar et al. World Journal of Pharmacy and Pharmaceutical Sciences HIBISCUS ROSA-SINENSIS: A REVIEW ON ORNAMENTAL PLANT Pekamwar S. S.*, Kalyankar T.M., Jadhav A.C. Department of Pharmaceutical Chemistry, School of Pharmacy, S R T M University,  Nanded- 431606 (MS) India. ABSTRACT  Nature has been a source of medicinal agents for thousands of year and a large number of drugs have been isolated from natural sources. Higher plants, as source of medicinal compounds, have continued to  play an important role in the maintenance of human health since ancient times. Over 50% of all modern clinical drugs are of natural  product srcin and have significant role in drug development programs in the pharmaceutical industry. Hibiscus rosa-sinensis, an ornamental  plant; posses different pharmacological activities & is used for treatment of different diseases. A review of pharmacological potential of  Hibiscus rosa-sinensis  plant is discussed in brief in this article. KEYWORDS:    Hibiscus rosa-sinensis , phytochemistry,  pharmacology. INTRODUCTION  Nature has been a source of medicinal agents for thoughts of years and a remarkable number of drugs have been isolated from natural source. Over the years, WHO advocated traditional medicines as safe remedies for aliments of both microbial and non-microbial srcins.  [1]  “World Health Organization” has recommended that traditional health and folk medicine systems are proved to be more efficient in health problems worldwide. India is one of the nations blessed with a rich heritage of traditional medical systems and rich biodiversity to complement the herbal needs of the treatment administered by these conventional medical systems. The accepted Indian systems of medicine are Ayurveda, Unani and Siddha, which uses herbs and natural resources in the formulations.  [2]     WWOORRLLDD JJOOUURRNN A  A LL OOFF PPHH A  A RRMM A  A CC Y  Y  A  A NNDD PPHH A  A RRMM A  A CCEEUUTTIICC A  A LL SSCCIIEENNCCEESS   V  V oolluummee 22,, IIssssuuee 66,, 44771199--44772277.. RReevviieeww A  A rrttiiccllee IISSSSNN 2278 – 4357    Article Received on 03 September 2013, Revised on 27 October 2013, Accepted on 14 November 2013 *Correspondence for Author: *Dr. S. S. Pekamwar, Director, School of Pharmacy, S R T M University,  Nanded-431606 (MS) India 4720   Pekamwar et al. World Journal of Pharmacy and Pharmaceutical Sciences  Hibiscus rosa sinensis  L (Malvaceae) is an ornamental plant often a hedge or fence plant. It is native to china and is also seen in India and Philippines. This plant having several forms and varying colors of flowers. This is a national flower of Malaysia.  [3] Figure 1: Hibiscus rosa sinensis Plant Scientific Classification Kingdom - Plantae Subkingdom - Tracheobionta Super division - Spermatophyta Division - Magnoliophyta Class - Magnoliopsida Subclass - Dilleniidae Order - Malvales Family - Malvaceae Genus - Hibiscus   Species -  Hibiscus rosa-sinensis PHYTOCHEMICAL REVIEW Different extract of  Hibiscus rosa-sinensis  plant revealed the presence of alkaloids, glycosides, fatty materials, reducing sugars, resin, sterols and the lack of tannins and Saponins. Isolation of β -sitosterol, taraxeryl acetate and four uncharacterized compounds which included an alkaloid and three sterols has been reported in the leaves. The leaves of  Hibiscus rosa-sinensis  were also investigated for their fatty alcohol, fatty acids and hydrocarbon content. Two cyclic acids viz., malvalic and sterculic are also identified.  [2] 4721   Pekamwar et al. World Journal of Pharmacy and Pharmaceutical Sciences Flowers contain vitamins, flavonoids, ascorbic acid, niacin, riboflavin, thiamine and cyaniding diglucoside. Quercetin-3-diglucoside, cyanidin-3-sophoroside-5-glycosides, 3, 7-diglucoside, cyanidin-3, 5-diglucoside have been isolated from deep yellow flowers.  [4]   Table 1: Phytochemical Review . Plant part Constituent reported 1 Flowers [5]  Thiamine, Riboflavin, Niacin and Ascorbic acid, Apigenidin, citric acid, fructose, glucose, oxalic acid, pelargonidin, quercetin. 2 Leaves [2]  Alkaloids, glycosides, reducing sugars, fatty materials, resin and sterols, Fatty acids, fatty alcohol, and hydrocarbon, sterculic and malvalic acid. 3 Stems [6]  Teraxeryl acetate, ß-sitosterol and the cyclicacids sterculic and malvalic acids. 4 Roots [7] Glycosides, tannins, phytosterols, fixed oils, fats, proteins, amino acids, flavonoids, Saponins, gums and mucilage. PHARMACOLOGICAL REVIEW  Hibiscus rosa sinensis (Malvaceae) is a perennial ornamental shrub available throughout   India. Various parts of this plant like flowers, leaves and roots have been known to possess medicinal properties like oral contraceptive, laxative, aphrodisiac, menorrhagic etc.  [8] Several articles and ancient literature have shown that the flowers of this plant possess antifertility activity.  [9]  The aqueous ethanolic extract of aerial parts of this plant was reported for its use in constipation and diarrhea.  [10] In traditional medicine, the leaves of the plant are used in fatigue and skin disease. Powdered root of the plant is given for menorrhagia and the fresh root juice for gonorrhea.  [11]  Flowers of the plant are used in diabetes, epilepsy,  bronchial catarrh and leprosy.  [12, 13] An infusion of the petal is widely used in Ayurvedic medicine in India as a demulcent refrigerant drink in fever   [14]  and decoction is given in bronchial catarrh.  [15]  Previous studies showed that the plant possess anti-phologistic, anti-diarrhetic and anticomplementary activity. [16] 4722   Pekamwar et al. World Journal of Pharmacy and Pharmaceutical Sciences It has been reported that the plant flower possess anti-spermatogenic and androgenic  [17]  anti-tumour activity.  [18]  The use of flower to treat heart disorders and anti-diabetic activity has also been confirmed.  [19, 20] Table 2: Pharmacological Review   Sr no Plant part Activity reported Model used Remark 1 Flower Antidiabetic Activity Steptozotocin induced  [21]  Found to be active Alloxan induced  [22]  Found to be active   Hair growth potential In vivo & in vitro methods [23]  Exits potency Anticonvulsive Activity Mice [24]  The brain content of GABA & serotonin were raised. Antifertility Activity Rats [25]  Antifertility effects in rats Abortifacient Activity Rats [26]  A dose of 186mg/kg were active Antiestrogenic Activity Albino rats [27]  A reduction in weights of the  pituitary, ovary & uterus. Guinea pigs [28]  Found to be active. Anti-implantation Activity Female albino rats [29]  Leading to 80% reduction In the implantation site on 10th day of  pregnancy. Antilithiatic potential In vitro assay [30]  A very good inhibitory effect against crystal nucleation, growth
We Need Your Support
Thank you for visiting our website and your interest in our free products and services. We are nonprofit website to share and download documents. To the running of this website, we need your help to support us.

Thanks to everyone for your continued support.

No, Thanks

We need your sign to support Project to invent "SMART AND CONTROLLABLE REFLECTIVE BALLOONS" to cover the Sun and Save Our Earth.

More details...

Sign Now!

We are very appreciated for your Prompt Action!